How Do Skin Whiteners Work? & other questions….

How Do Skin Whiteners Work?

Skin whitening creams contain ingredients that act to slow the production of melanin in the skin’s outer layer.

Melanin is a brown pigment produced in the melanocytes in the skin. Melanin is the body’s natural protection against the harmful effects of UV rays, however, an over production of melanin (hyper-pigmentation) can cause uneven skin tones and other skin disorders.

Skin bleaching agents act to reduce the action of the enzyme, tyrosinase, which controls the rate of melanin production in the skin.

Products that contain effective ingredients can help to treat the problems associated with hyper-pigmentation, however, chemical-based skin whiteners can be potentially dangerous and carries the significant health risks with extended use.


What Skin Whitening Ingredients Should We Avoid?

Chemicals traditionally used in skin whitening products can include hydroquinine, mercury and steroids. While the use of these chemicals has been banned in some countries, ingredients like hydroquinine may still be prescribed by physicians.

The biggest danger of exposing the skin and body to these toxic chemicals is that, over time, they can produce adverse side effects and serious health concerns including skin discoloration, malfunctions of the nervous system and internal organs and an increased risk of cancer.


Hydroquinone [C6H4(OH)2] is a toxic chemical that is used in black and white film processing, manufacturing rubber and is found in some hair dyes. Hydroquinine is used in skin lightening creams and lotions because it is an effective bleaching agent, slowing the production of the tyrosinase enzyme and reducing the amount of melanin formed.

While we do not know the full extent of the health risks hydroquinone poses, it is considered to be cytotoxic (toxic to cells), mutagenic and carcinogenic (cancer causing). Hydroquinine is thought to increase the risk of complications such as thyroid disorders, liver disease and adrenal dysfunction. It has been banned for sale as a skin lightener in Europe, Japan, and Australia and many groups are calling for the FDA to ban this chemical in the US.

A ban was proposed by the FDA back in 2006 but currently skin-lightening products that contain 2 % hydroquinone can be sold over-the-counter and products that contain up to 4 % hydroquinone can be obtained by prescription from a physician.

Common side effects reported from the use of hydroquinine creams include skin rashes, burning skin irritation, excessive redness and a dryness or cracking of the skin.

If used for extended periods of time, hydroquinone can sometimes induce a condition known as “ochronosis.” People with ochronosis can show a blue-black darkening in certain areas of the skin.

Like other pigment-reducing complexes, hydroquinone can make your skin more susceptible to the sun’s UV rays. This can lead to serious sunburn and an increased risk of certain types of skin cancer.


In August 2013 the Food and Drug Administration (FDA) issued a warning to consumers advising them not to use skin creams, beauty soaps or lotions that might contain mercury due to the dangers of mercury poisoning.  The FDA first banned the use of mercury in skin-bleaching and lightening products back in 1990 but the regulatory office has since found that mercury was being used as an ingredient in some products that were manufactured abroad and sold illegally in the United States.

Mercury is a toxic chemical that is readily absorbed into the body but it is not easily removed. When mercury is used for skin whitening the initial side effects can include skin rashes, skin discoloration and scarring. Long term exposure to mercury can have more serious health consequences.

The World Health Organization advises that using mercury on a long term basis can damage the kidneys and the nervous system. It can also cause depression or psychosis and interfere with the development of the brain in unborn children and very young children.

The FDA recommends that you read the label of any skin lightening creams you use. Products containing mercury will have the words “mercury,” “mercurous chloride”, “mercuric,” “mercurio,” or “calomel.”  If there is no label or list of ingredients do not use that product.


Unfortunately, many skin-lightening creams contain illegal compounds which can include high-dose steroids. Although steroids can be useful in treating inflammation of the skin caused by diseases such as eczema, psoriasis or dermatitis, they were never intended for skin lightening use.

When steroids are prescribed this take place under the supervision of a skin specialist and the usage is generally minimized to a few short weeks.

While topical corticosteroids can appear to lighten the skin very quickly, this is because they act as “vaso-constrictors”. This means the blood vessels in the area treated will become constricted (narrow) and the flow of blood will be slowed, giving the skin a whiter appearance.

Steroids can also slow the process of cell regeneration so less melanocytes are formed, leading to a decline in melanin production. The negative side of slowing the skin’s natural cell renewal is that the epidermis (outer skin layer) can becomes thinner and many people complain of the appearance of green veins in the skin.

Unmonitored use of high-dose steroids can lead to many problems. The thinning effect on the skin can increase the risk of physical damage to the skin. The skin can become more susceptible to chemical and environmental factors and there will be an increased risk of sun damage and additional pigmentation problems.

The high doses of steroids found in the illegal skin whitening creams can also interfere with the body’s hormone levels and, in extreme cases, can result in disorders such as Cushings syndrome which affects the adrenal gland.


Are There Natural Alternatives for Skin Whitening?

Since many chemical-based skin lighteners have now been found to have serious health concerns, researchers and skin care companies have been prompted to look for safer alternatives for their consumers which is good news for us!

Extensive testing of many plant species has led to the discovery of a number of all natural lightening ingredients that act to suppress melanin production, in the same way as their chemical-based counterparts, but they are non-toxic and do not carry the risk of serious side effects.

While natural skin lightening products still vary they will generally include ingredients such as alpha arbutin, emblica, liquorice, mulberry extract, kojic acid d/p or Vitamin C.

Parisa Beauty Care cream (developed by Elixir Herbal Care, Karachi Pakistan) is a good example of a plant-based lightening cream that utilizes a number of these natural “pigment reducers” – ingredients that are clinically proven to inhibit melanin production in the skin. Natural skin lighteners have been found to achieve very good results without the risk of serious side effects and offer a great alternative for people who want to avoid chemical-based products.

What are the Causes of excessive Melanin Production?

  • Hyper pigmentation
  • Over exposure to sun
  • Skin disorders
  • Malnutrition
  • Vitamin deficiency
  • Adrenal disorders
  • Liver disorder
  • Hormonal changes

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